Eleva’s drug candidate to be examined for use in Covid-19 treatment

Eleva, a manufacturer of superior biologics, is exploring the potential of one of its drug candidates for first-in-line therapy of Covid-19. The compound, factor H, is part of the complement system, which is believed to affect the severity of the course of Covid-19. Eleva has developed factor H previously for a different indication and taken it through pre-clinical stages.

The complement system is a vital part of the immune system. It recognizes and destroys pathogens and protects the body’s own cells with a special component, factor H. Insufficient amounts of factor H lead to excessive inflammation and risk of tissue damage. Emerging evidence suggests that the lung tissue decay observed in severe cases of Covid-19 could be caused by this unregulated inflammation. Current means to inhibit this process use artificial antibodies that block the pathway altogether, stopping the inactivation of pathogens and causing a significant risk of infection. Conversely, supplemented factor H allows for regu lated defence while protecting the host cells.

Andreas Schaaf, CEO of Eleva, says: “Unlocking novel therapies is our mission. This path deserves to be explored and may lead to effective treatment of Covid-19.”

Eleva has previously developed recombinant factor H for glomerulopathy and taken it through pre-clinical stages. Studies have indicated a significant reduction in inflammation and tissue damage when factor H was supplemented. Eleva is now looking to accelerate the Covid-19-specific evaluation with a pharmaceutical partner.

About Eleva

Eleva develops novel biological therapies with its pharmaceutical partners. The privately-held company leverages its unique moss-based production platform to produce supreme biologics like antibodies, replacement enzymes, or fusion toxins. Eleva has successfully developed drug candidates into clinical phases. Press contact

eleva GmbH

Fabienne Zeitter

pr@elevabiologics.com

+49 761 470 99 0

www.elevabiologics.com

 

SENDING PRESS RELEASES

I want to receive press releases with the same keywords as this article:

Keywords

Germany-health-pharmaceutical-eleva GmbH

Category

Health, medical treatment, pharmaceuticals
Chemical, pharmaceutical and cosmetic industry

Region

Europe, EU, NATO

Photograph

 
 

Important notice

Subscribers please note that material bearing the label "PROTEXT" is not part of CTK's news service and is not to be published under the "CTK" label. Protext is a commercial service providing distribution of press releases from clients, who are identified in the text of Protext reports and who bear full responsibility for their contents.